quantitative high-resolution computed tomography (hrct) metrics (Imbio LLC)
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Quantitative High Resolution Computed Tomography (Hrct) Metrics, supplied by Imbio LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: Weak to no correlation between quantitative high-resolution computed tomography metrics and lung function change in fibrotic diseases
Journal: ERJ Open Research
doi: 10.1183/23120541.00210-2023
Figure Legend Snippet: Patients’ clinical characteristics and high-resolution computed tomography metrics at baseline.
Techniques Used: Computed Tomography
Figure Legend Snippet: Forest plot for the Spearman correlation coefficient with 95% confidence intervals between forced vital capacity (FVC) and high-resolution computed tomography (HRCT) metrics at baseline. qILD: quantification of interstitial lung disease; PFD: pirfenidone.
Techniques Used: Computed Tomography
Figure Legend Snippet: Forest plot for the Spearman correlation coefficient with 95% confidence intervals between forced vital capacity (FVC) and high-resolution computed tomography (HRCT) metrics. qILD: quantification of interstitial lung disease; PFD: pirfenidone.
Techniques Used: Computed Tomography
Figure Legend Snippet: Scatterplot with a smooth line using a generalised additive model between baseline high-resolution computed tomography (HRCT) metrics and forced vital capacity (FVC) slope. The shaded area represents 95% confidence interval of the smooth line. qILD: quantification of interstitial lung disease; PFD: pirfenidone.
Techniques Used: Computed Tomography
Figure Legend Snippet: Adjusted R 2 of high-resolution computed tomography (HRCT) metrics in predicting forced vital capacity (FVC) slope after adjusting baseline clinical characteristics. a) Tocilizumab phase 3 in systemic sclerosis (SSc) (n=86); two patients were not included in the analysis as they did not have post-baseline measurements; b) zinpentraxin alfa phase 2 in idiopathic pulmonary fibrosis (IPF) (n=39); c) lebrikizumab phase 2 in IPF cohort A (n=38); d) lebrikizumab phase 2 in IPF cohort B (n=106). Each HRCT metric was sorted based on their adjusted R 2 level. The dashed line is the adjusted R 2 from the base model, and each dot represents the adjusted R 2 from the base model with the added HRCT metric. Base model: FVC slope ∼ baseline FVC + sex + age + height; added model: FVC slope ∼ baseline FVC + sex + age + height + HRCT. qILD: quantification of interstitial lung disease; PFD: pirfenidone.
Techniques Used: Computed Tomography
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